Αρχή φόρμας

The extracellular matrix as a multitasking player in disease.

Theocharis AD, Manou D, Karamanos NK.

FEBS J. 2019 Mar 25. doi: 10.1111/febs.14818. [Epub ahead of print] Review.

The Complex Interplay Between Extracellular Matrix and Cells in Tissues.

Manou D, Caon I, Bouris P, Triantaphyllidou IE, Giaroni C, Passi A, Karamanos NK, Vigetti D, Theocharis AD.

Methods Mol Biol. 2019;1952:1-20. doi: 10.1007/978-1-4939-9133-4_1.

Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics.

Karamanos NK, Piperigkou Z, Theocharis AD, Watanabe H, Franchi M, Baud S, Brézillon S, Götte M, Passi A, Vigetti D, Ricard-Blum S, Sanderson RD, Neill T, Iozzo RV.

Chem Rev. 2018 Sep 26;118(18):9152-9232. doi: 10.1021/acs.chemrev.8b00354. Epub 2018 Sep 11.

Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases.

Karamanos NK, Theocharis AD, Neill T, Iozzo RV.

Matrix Biol. 2019 Jan;75-76:1-11. doi: 10.1016/j.matbio.2018.08.007. Epub 2018 Aug 18. Review.

Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling.

Bouris P, Manou D, Sopaki-Valalaki A, Kolokotroni A, Moustakas A, Kapoor A, Iozzo RV, Karamanos NK, Theocharis AD.

Matrix Biol. 2018 Dec;74:35-51. doi: 10.1016/j.matbio.2018.05.011. Epub 2018 May 26.

Strategies to Target Matrix Metalloproteinases as Therapeutic Approach in Cancer.

Piperigkou Z, Manou D, Karamanou K, Theocharis AD.

Methods Mol Biol. 2018;1731:325-348. doi: 10.1007/978-1-4939-7595-2_27. Review.

Proteoglycans remodeling in cancer: Underlying molecular mechanisms.

Theocharis AD, Karamanos NK.

Matrix Biol. 2019 Jan;75-76:220-259. doi: 10.1016/j.matbio.2017.10.008. Epub 2017 Nov 8. Review.

Insights into the key roles of epigenetics in matrix macromolecules-associated wound healing.

Piperigkou Z, Götte M, Theocharis AD, Karamanos NK.

Adv Drug Deliv Rev. 2018 Apr;129:16-36. doi: 10.1016/j.addr.2017.10.008. Epub 2017 Oct 24. Review.

IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules.

Afratis NA, Bouris P, Skandalis SS, Multhaupt HA, Couchman JR, Theocharis AD, Karamanos NK.

Sci Rep. 2017 Jan 12;7:40138. doi: 10.1038/srep40138.

Syndecans - key regulators of cell signaling and biological functions.

Afratis NA, Nikitovic D, Multhaupt HA, Theocharis AD, Couchman JR, Karamanos NK.

FEBS J. 2017 Jan;284(1):27-41. doi: 10.1111/febs.13940. Epub 2016 Nov 18. Review.

The role of heparins and nano-heparins as therapeutic tool in breast cancer.

Afratis NA, Karamanou K, Piperigkou Z, Vynios DH, Theocharis AD.

Glycoconj J. 2017 Jun;34(3):299-307. doi: 10.1007/s10719-016-9742-7. Epub 2016 Oct 24. Review.

Estrogen receptor beta modulates breast cancer cells functional properties, signaling and expression of matrix molecules.

Piperigkou Z, Bouris P, Onisto M, Franchi M, Kletsas D, Theocharis AD, Karamanos NK.

Matrix Biol. 2016 Dec;56:4-23. doi: 10.1016/j.matbio.2016.05.003. Epub 2016 May 11.

Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines.

Korpetinou A, Papachristou DJ, Lampropoulou A, Bouris P, Labropoulou VT, Noulas A, Karamanos NK, Theocharis AD.

Biomed Res Int. 2015;2015:690721. doi: 10.1155/2015/690721. Epub 2015 Oct 25.

Extracellular matrix structure.

Theocharis AD, Skandalis SS, Gialeli C, Karamanos NK.

Adv Drug Deliv Rev. 2016 Feb 1;97:4-27. doi: 10.1016/j.addr.2015.11.001. Epub 2015 Nov 10. Review.

Epidermal growth factor receptor status and Notch inhibition in non-small cell lung cancer cells.

Giannopoulou E, Nikolakopoulos A, Kotsirilou D, Lampropoulou A, Raftopoulou S, Papadimitriou E, Theocharis AD, Makatsoris T, Fasseas K, Kalofonos HP.

J Biomed Sci. 2015 Oct 24;22:98. doi: 10.1186/s12929-015-0196-1.

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.

Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, Karamanos NK.

Biochim Biophys Acta. 2015 Apr;1855(2):276-300. doi: 10.1016/j.bbcan.2015.03.006. Epub 2015 Mar 28. Review.

ADAMTS expression in colorectal cancer.

Filou S, Korpetinou A, Kyriakopoulou D, Bounias D, Stavropoulos M, Ravazoula P, Papachristou DJ, Theocharis AD, Vynios DH.

PLoS One. 2015 Mar 18;10(3):e0121209. doi: 10.1371/journal.pone.0121209. eCollection 2015.

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Bouris P, Skandalis SS, Piperigkou Z, Afratis N, Karamanou K, Aletras AJ, Moustakas A, Theocharis AD, Karamanos NK.

Matrix Biol. 2015 Apr;43:42-60. doi: 10.1016/j.matbio.2015.02.008. Epub 2015 Feb 27.

Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.

Theocharis AD, Gialeli C, Bouris P, Giannopoulou E, Skandalis SS, Aletras AJ, Iozzo RV, Karamanos NK.

FEBS J. 2014 Nov;281(22):5023-42. doi: 10.1111/febs.12927. Epub 2014 Nov 6. Review.

Validated capillary electrophoretic assays for disaccharide composition analysis of galactosaminoglycans in biologic samples and drugs/nutraceuticals.

Asimakopoulou AP, Malavaki C, Afratis NA, Theocharis AD, Lamari FN, Karamanos NK.

Methods Mol Biol. 2015;1229:129-41. doi: 10.1007/978-1-4939-1714-3_13.

Advances and advantages of nanomedicine in the pharmacological targeting of hyaluronan-CD44 interactions and signaling in cancer.

Skandalis SS, Gialeli C, Theocharis AD, Karamanos NK.

Adv Cancer Res. 2014;123:277-317. doi: 10.1016/B978-0-12-800092-2.00011-3. Review.

EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.

Ellina MI, Bouris P, Aletras AJ, Theocharis AD, Kletsas D, Karamanos NK.

Biochim Biophys Acta. 2014 Aug;1840(8):2651-61. doi: 10.1016/j.bbagen.2014.04.019. Epub 2014 May 2.

EMMPRIN/CD147-encriched membrane vesicles released from malignant human testicular germ cells increase MMP production through tumor-stroma interaction.

Milia-Argeiti E, Mourah S, Vallée B, Huet E, Karamanos NK, Theocharis AD, Menashi S.

Biochim Biophys Acta. 2014 Aug;1840(8):2581-8. doi: 10.1016/j.bbagen.2014.02.026. Epub 2014 Mar 6.

Syndecans as modulators and potential pharmacological targets in cancer progression.

Barbouri D, Afratis N, Gialeli C, Vynios DH, Theocharis AD, Karamanos NK.

Front Oncol. 2014 Feb 3;4:4. doi: 10.3389/fonc.2014.00004. eCollection 2014. Review.

Serglycin: at the crossroad of inflammation and malignancy.

Korpetinou A, Skandalis SS, Labropoulou VT, Smirlaki G, Noulas A, Karamanos NK, Theocharis AD.

Front Oncol. 2014 Jan 13;3:327. doi: 10.3389/fonc.2013.00327. eCollection 2014 Jan 13. Review.

Cellular microenvironment in human pathologies.

Vigetti D, Götte M, Pavão MS, Theocharis AD.

Biomed Res Int. 2013;2013:946958. doi: 10.1155/2013/946958. Epub 2013 Nov 7. No abstract available.

Serglycin is implicated in the promotion of aggressive phenotype of breast cancer cells.

Korpetinou A, Skandalis SS, Moustakas A, Happonen KE, Tveit H, Prydz K, Labropoulou VT, Giannopoulou E, Kalofonos HP, Blom AM, Karamanos NK, Theocharis AD.

PLoS One. 2013 Oct 31;8(10):e78157. doi: 10.1371/journal.pone.0078157. eCollection 2013.

Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans.

Skandalis SS, Afratis N, Smirlaki G, Nikitovic D, Theocharis AD, Tzanakakis GN, Karamanos NK.

Matrix Biol. 2014 Apr;35:182-93. doi: 10.1016/j.matbio.2013.09.002. Epub 2013 Sep 21. Review.

PDGF/PDGFR signaling and targeting in cancer growth and progression: Focus on tumor microenvironment and cancer-associated fibroblasts.

Gialeli C, Nikitovic D, Kletsas D, Theocharis AD, Tzanakakis GN, Karamanos NK.

Curr Pharm Des. 2014;20(17):2843-8. Review.

Expression of syndecan-4 and correlation with metastatic potential in testicular germ cell tumours.

Labropoulou VT, Skandalis SS, Ravazoula P, Perimenis P, Karamanos NK, Kalofonos HP, Theocharis AD.

Biomed Res Int. 2013;2013:214864. doi: 10.1155/2013/214864. Epub 2013 Jun 15.

In vitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican.

Malla N, Berg E, Theocharis AD, Svineng G, Uhlin-Hansen L, Winberg JO.

FEBS J. 2013 Jun;280(12):2870-87. doi: 10.1111/febs.12291. Epub 2013 May 9.

Preclinical evaluation of zoledronate using an in vitro mimetic cellular model for breast cancer metastatic bone disease.

Dedes PG, Kanakis I, Gialeli Ch, Theocharis AD, Tsegenidis T, Kletsas D, Tzanakakis GN, Karamanos NK.

Biochim Biophys Acta. 2013 Jun;1830(6):3625-34. doi: 10.1016/j.bbagen.2013.01.020. Epub 2013 Feb 5.

Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases.

Skliris A, Labropoulou VT, Papachristou DJ, Aletras A, Karamanos NK, Theocharis AD.

FEBS J. 2013 May;280(10):2342-52. doi: 10.1111/febs.12179. Epub 2013 Mar 1.

Imatinib as a key inhibitor of the platelet-derived growth factor receptor mediated expression of cell surface heparan sulfate proteoglycans and functional properties of breast cancer cells.

Malavaki CJ, Roussidis AE, Gialeli C, Kletsas D, Tsegenidis T, Theocharis AD, Tzanakakis GN, Karamanos NK.

FEBS J. 2013 May;280(10):2477-89. doi: 10.1111/febs.12163. Epub 2013 Feb 27.

Evaluation of the coordinated actions of estrogen receptors with epidermal growth factor receptor and insulin-like growth factor receptor in the expression of cell surface heparan sulfate proteoglycans and cell motility in breast cancer cells.

Tsonis AI, Afratis N, Gialeli C, Ellina MI, Piperigkou Z, Skandalis SS, Theocharis AD, Tzanakakis GN, Karamanos NK.

FEBS J. 2013 May;280(10):2248-59. doi: 10.1111/febs.12162. Epub 2013 Feb 27.

Efficient TGFβ-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2.

Porsch H, Bernert B, Mehić M, Theocharis AD, Heldin CH, Heldin P.

Oncogene. 2013 Sep 12;32(37):4355-65. doi: 10.1038/onc.2012.475. Epub 2012 Oct 29.

Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.

Gialeli Ch, Theocharis AD, Kletsas D, Tzanakakis GN, Karamanos NK.

Invest New Drugs. 2013 Jun;31(3):516-24. doi: 10.1007/s10637-012-9875-x. Epub 2012 Sep 6.

Expression of matrix macromolecules and functional properties of breast cancer cells are modulated by the bisphosphonate zoledronic acid.

Dedes PG, Gialeli Ch, Tsonis AI, Kanakis I, Theocharis AD, Kletsas D, Tzanakakis GN, Karamanos NK.

Biochim Biophys Acta. 2012 Dec;1820(12):1926-39. doi: 10.1016/j.bbagen.2012.07.013. Epub 2012 Aug 3.

Imbalance of MMP-2 and MMP-9 expression versus TIMP-1 and TIMP-2 reflects increased invasiveness of human testicular germ cell tumours.

Milia-Argeiti E, Huet E, Labropoulou VT, Mourah S, Fenichel P, Karamanos NK, Menashi S, Theocharis AD.

Int J Androl. 2012 Dec;35(6):835-44. doi: 10.1111/j.1365-2605.2012.01289.x. Epub 2012 Jun 19.

Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules.

Skandalis SS, Aletras AJ, Gialeli C, Theocharis AD, Afratis N, Tzanakakis GN, Karamanos NK.

Curr Mol Med. 2012 Sep;12(8):1068-82. Review.

Glycosaminoglycans: key players in cancer cell biology and treatment.

Afratis N, Gialeli C, Nikitovic D, Tsegenidis T, Karousou E, Theocharis AD, Pavão MS, Tzanakakis GN, Karamanos NK.

FEBS J. 2012 Apr;279(7):1177-97. doi: 10.1111/j.1742-4658.2012.08529.x. Epub 2012 Mar 12. Review.

Versican but not decorin accumulation is related to malignancy in mammographically detected high density and malignant-appearing microcalcifications in non-palpable breast carcinomas.

Skandalis SS, Labropoulou VT, Ravazoula P, Likaki-Karatza E, Dobra K, Kalofonos HP, Karamanos NK, Theocharis AD.

BMC Cancer. 2011 Jul 26;11:314. doi: 10.1186/1471-2407-11-314.

Pathophysiology and pharmacological targeting of tumor-induced bone disease: current status and emerging therapeutic interventions.

Labropoulou VT, Theocharis AD, Symeonidis A, Skandalis SS, Karamanos NK, Kalofonos HP.

Curr Med Chem. 2011;18(11):1584-98. Review.

Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma.

Skliris A, Happonen KE, Terpos E, Labropoulou V, Børset M, Heinegård D, Blom AM, Theocharis AD.

Eur J Immunol. 2011 Feb;41(2):437-49. doi: 10.1002/eji.201040429. Epub 2010 Dec 30.

Heparan sulfate: biological significance, tools for biochemical analysis and structural characterization.

Malavaki CJ, Theocharis AD, Lamari FN, Kanakis I, Tsegenidis T, Tzanakakis GN, Karamanos NK.

Biomed Chromatogr. 2011 Jan;25(1-2):11-20. doi: 10.1002/bmc.1536. Review.

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting.

Gialeli C, Theocharis AD, Karamanos NK.

FEBS J. 2011 Jan;278(1):16-27. doi: 10.1111/j.1742-4658.2010.07919.x. Epub 2010 Nov 19. Review.

Glycosaminoglycans as key molecules in atherosclerosis: the role of versican and hyaluronan.

Karangelis DE, Kanakis I, Asimakopoulou AP, Karousou E, Passi A, Theocharis AD, Triposkiadis F, Tsilimingas NB, Karamanos NK.

Curr Med Chem. 2010;17(33):4018-26. Review.

Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.

Theocharis AD, Skandalis SS, Tzanakakis GN, Karamanos NK.

FEBS J. 2010 Oct;277(19):3904-23. doi: 10.1111/j.1742-4658.2010.07800.x. Epub 2010 Aug 31. Review.

Estradiol-estrogen receptor: a key interplay of the expression of syndecan-2 and metalloproteinase-9 in breast cancer cells.

Kousidou OCh, Berdiaki A, Kletsas D, Zafiropoulos A, Theocharis AD, Tzanakakis GN, Karamanos NK.

Mol Oncol. 2008 Oct;2(3):223-32. doi: 10.1016/j.molonc.2008.06.002. Epub 2008 Jun 18.

A comparative biochemical analysis of glycosaminoglycans and proteoglycans in human orthotopic and heterotopic bone.

Mania VM, Kallivokas AG, Malavaki C, Asimakopoulou AP, Kanakis J, Theocharis AD, Klironomos G, Gatzounis G, Mouzaki A, Panagiotopoulos E, Karamanos NK.

IUBMB Life. 2009 Apr;61(4):447-52. doi: 10.1002/iub.167.

Keratan sulfate-containing proteoglycans in sheep brain with particular reference to phosphacan and synaptic vesicle proteoglycan isoforms.

Sinouris EA, Skandalis SS, Kilia V, Theocharis AD, Theocharis DA, Ravazoula P, Vynios DH, Papageorgakopoulou N.

Biomed Chromatogr. 2009 May;23(5):455-63. doi: 10.1002/bmc.1127.

Versican in health and disease.

Theocharis AD.

Connect Tissue Res. 2008;49(3):230-4. doi: 10.1080/03008200802147571.

Hyaluronan and chondroitin sulfate proteoglycans in the supramolecular organization of the mammalian vitreous body.

Theocharis DA, Skandalis SS, Noulas AV, Papageorgakopoulou N, Theocharis AD, Karamanos NK.

Connect Tissue Res. 2008;49(3):124-8. doi: 10.1080/03008200802148496. Review.

The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents.

Asimakopoulou AP, Theocharis AD, Tzanakakis GN, Karamanos NK.

In Vivo. 2008 May-Jun;22(3):385-9. Review.

Glycosaminoglycan in cerebrum, cerebellum and brainstem of young sheep brain with particular reference to compositional and structural variations of chondroitin-dermatan sulfate and hyaluronan.

Kilia V, Skandalis SS, Theocharis AD, Theocharis DA, Karamanos NK, Papageorgakopoulou N.

Biomed Chromatogr. 2008 Sep;22(9):931-8. doi: 10.1002/bmc.1010.

Capillary electrophoresis for the quality control of chondroitin sulfates in raw materials and formulations.

Malavaki CJ, Asimakopoulou AP, Lamari FN, Theocharis AD, Tzanakakis GN, Karamanos NK.

Anal Biochem. 2008 Mar 1;374(1):213-20. Epub 2007 Nov 9.

The importance of c-Kit and PDGF receptors as potential targets for molecular therapy in breast cancer.

Roussidis AE, Theocharis AD, Tzanakakis GN, Karamanos NK.

Curr Med Chem. 2007;14(7):735-43. Review.

Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression.

Theocharis AD, Tsolakis I, Tzanakakis GN, Karamanos NK.

Adv Pharmacol. 2006;53:281-95. Review. No abstract available.

Versican but not decorin accumulation is related to metastatic potential and neovascularization in testicular germ cell tumours.

Labropoulou VT, Theocharis AD, Ravazoula P, Perimenis P, Hjerpe A, Karamanos NK, Kalofonos HP.

Histopathology. 2006 Dec;49(6):582-93.

Dietary manganese affects the concentration, composition and sulfation pattern of heparan sulfate glycosaminoglycans in Sprague-Dawley rat aorta.

Kalea AZ, Lamari FN, Theocharis AD, Schuschke DA, Karamanos NK, Klimis-Zacas DJ.

Biometals. 2006 Oct;19(5):535-46.

Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro.

Theocharis AD, Seidel C, Borset M, Dobra K, Baykov V, Labropoulou V, Kanakis I, Dalas E, Karamanos NK, Sundan A, Hjerpe A.

J Biol Chem. 2006 Nov 17;281(46):35116-28. Epub 2006 Jul 26.

Metabolism and biochemical/physiological roles of chondroitin sulfates: analysis of endogenous and supplemental chondroitin sulfates in blood circulation.

Lamari FN, Theocharis AD, Asimakopoulou AP, Malavaki CJ, Karamanos NK.

Biomed Chromatogr. 2006 Jun-Jul;20(6-7):539-50. Review.

The increased accumulation of structurally modified versican and decorin is related with the progression of laryngeal cancer.

Skandalis SS, Theocharis AD, Papageorgakopoulou N, Vynios DH, Theocharis DA.

Biochimie. 2006 Sep;88(9):1135-43. Epub 2006 Apr 25.

Cartilage aggrecan undergoes significant compositional and structural alterations during laryngeal cancer.

Skandalis SS, Theocharis AD, Vynios DH, Papageorgakopoulou N, Hjerpe A, Karamanos NK, Theocharis DA.

Biochim Biophys Acta. 2006 Jul;1760(7):1046-53. Epub 2006 Mar 9.

Transforming growth factor-beta as a key molecule triggering the expression of versican isoforms v0 and v1, hyaluronan synthase-2 and synthesis of hyaluronan in malignant osteosarcoma cells.

Nikitovic D, Zafiropoulos A, Katonis P, Tsatsakis A, Theocharis AD, Karamanos NK, Tzanakakis GN.

IUBMB Life. 2006 Jan;58(1):47-53.

Immunization with specific polysaccharide antigen reduces alterations in corneal proteoglycans during experimental slime-producing Staphylococcus epidermidis keratitis.

Georgakopoulos CD, Exarchou AM, Gartaganis SP, Kolonitsiou F, Anastassiou ED, Dimitracopoulos G, Hjerpe A, Theocharis AD, Karamanos NK.

Curr Eye Res. 2006 Feb;31(2):137-46.

Wild blueberry (Vaccinium angustifolium) consumption affects the composition and structure of glycosaminoglycans in Sprague-Dawley rat aorta.

Kalea AZ, Lamari FN, Theocharis AD, Cordopatis P, Schuschke DA, Karamanos NK, Klimis-Zacas DJ.

J Nutr Biochem. 2006 Feb;17(2):109-16. Epub 2005 Jun 20.

Signal transduction by IL-2 and its receptors as target in treatment of rheumatoid arthritis.

Kozanidou VI, Theocharis AD, Georgiadis A, Voulgari PV, Drosos AA, Karamanos NK.

Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar;5(1):41-50. Review.

Genistein suppresses the invasive potential of human breast cancer cells through transcriptional regulation of metalloproteinases and their tissue inhibitors.

Kousidou OC, Mitropoulou TN, Roussidis AE, Kletsas D, Theocharis AD, Karamanos NK.

Int J Oncol. 2005 Apr;26(4):1101-9.

Expression of MMPs and TIMPs genes in human breast cancer epithelial cells depends on cell culture conditions and is associated with their invasive potential.

Kousidou OC, Roussidis AE, Theocharis AD, Karamanos NK.

Anticancer Res. 2004 Nov-Dec;24(6):4025-30.

STI571 as a potent inhibitor of growth and invasiveness of human epithelial breast cancer cells.

Roussidis AE, Mitropoulou TN, Theocharis AD, Kiamouris C, Papadopoulos S, Kletsas D, Karamanos NK.

Anticancer Res. 2004 May-Jun;24(3a):1445-7.

Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinoma.

Skandalis SS, Theocharis AD, Theocharis DA, Papadas T, Vynios DH, Papageorgakopoulou N.

Biochim Biophys Acta. 2004 Jun 28;1689(2):152-61.

IGF-I affects glycosaminoglycan/proteoglycan synthesis in breast cancer cells through tyrosine kinase-dependent and -independent pathways.

Mitropoulou TN, Theocharis AD, Nikitovic D, Karamanos NK, Tzanakakis GN.

Biochimie. 2004 Apr-May;86(4-5):251-9.

Proteoglycans in human laryngeal cartilage. Identification of proteoglycan types in successive cartilage extracts with particular reference to aggregating proteoglycans.

Skandalis SS, Theocharis AD, Vynios DH, Theocharis DA, Papageorgakopoulou N.

Biochimie. 2004 Mar;86(3):221-9.

A sandwich ELISA for the estimation of human syndecan-2 and syndecan-4 in biological samples.

Seidel C, Gulyás M, David G, Dobra K, Theocharis AD, Hjerpe A.

J Pharm Biomed Anal. 2004 Mar 1;34(4):797-801.

Versican undergoes specific alterations in the fine molecular structure and organization in human aneurysmal abdominal aortas.

Theocharis AD, Tsolakis I, Hjerpe A, Karamanos NK.

Biomed Chromatogr. 2003 Sep;17(6):411-6.

Large matrix proteoglycans, versican and perlecan, are expressed and secreted by human leukemic monocytes.

Makatsori E, Lamari FN, Theocharis AD, Anagnostides S, Hjerpe A, Tsegenidis T, Karamanos NK.

Anticancer Res. 2003 Jul-Aug;23(4):3303-9.

Glycosaminoglycans in early chick embryo.

Skandalis SS, Theocharis AD, Papageorgakopoulou N, Zagris N.

Int J Dev Biol. 2003 May;47(4):311-4.

Occurrence and structural characterization of versican-like proteoglycan in human vitreous.

Theocharis AD, Papageorgakopoulou N, Feretis E, Theocharis DA.

Biochimie. 2002 Dec;84(12):1237-43.

Immunological studies of sheep brain keratan sulphate proteoglycans.

Papageorgakopoulou N, Theocharis AD, Skandalis SS, Vynios DH, Theocharis DA, Tsiganos CP.

Biochimie. 2002 Dec;84(12):1225-8.

Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinoma.

Theocharis AD, Vynios DH, Papageorgakopoulou N, Skandalis SS, Theocharis DA.

Int J Biochem Cell Biol. 2003 Mar;35(3):376-90.

Compositional and structural alterations of proteoglycans in human rectum carcinoma with special reference to versican and decorin.

Tsara ME, Theocharis AD, Theocharis DA.

Anticancer Res. 2002 Sep-Oct;22(5):2893-8.

Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aorta.

Theocharis AD, Theocharis DA, De Luca G, Hjerpe A, Karamanos NK.

Biochimie. 2002 Jul;84(7):667-74.

Decreased biglycan expression and differential decorin localization in human abdominal aortic aneurysms.

Theocharis AD, Karamanos NK.

Atherosclerosis. 2002 Dec;165(2):221-30.

Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin.

Theocharis AD.

Biochim Biophys Acta. 2002 Nov 20;1588(2):165-72.

Pig vitreous gel: macromolecular composition with particular reference to hyaluronan-binding proteoglycans.

Noulas AV, Theocharis AD, Feretis E, Papageorgakopoulou N, Karamanos NK, Theocharis DA.

Biochimie. 2002 Apr;84(4):295-302.

High-performance capillary electrophoretic analysis of hyaluronan and galactosaminoglycan-disaccharides in gastrointestinal carcinomas. Differential disaccharide composition as a possible tool-indicator for malignancies.

Theocharis AD, Theocharis DA.

Biomed Chromatogr. 2002 Apr;16(2):157-61.

Isolation and characterization of matrix proteoglycans from human nasal cartilage. Compositional and structural comparison between normal and scoliotic tissues.

Theocharis AD, Karamanos NK, Papageorgakopoulou N, Tsiganos CP, Theocharis DA.

Biochim Biophys Acta. 2002 Jan 15;1569(1-3):117-26.

Keratan sulphate in cerebrum, cerebellum and brainstem of sheep brain.

Papageorgakopoulou N, Theocharis AD, Skandalis SS, Vynios DH, Theocharis DA, Tsiganos CP.

Biochimie. 2001 Oct;83(10):973-8.

Characterization of glycosaminoglycans from human normal and scoliotic nasal cartilage with particular reference to dermatan sulfate.

Theocharis AD, Tsara ME, Papageorgakopoulou N, Vynios DH, Theocharis DA.

Biochim Biophys Acta. 2001 Oct 3;1528(2-3):81-8.

Identification, quantification and fine structural characterization of glycosaminoglycans from uterine leiomyoma and normal myometrium.

Mitropoulou TN, Theocharis AD, Stagiannis KD, Karamanos NK.

Biochimie. 2001 Jun;83(6):529-36.

Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0).

Theocharis AD, Tsolakis I, Hjerpe A, Karamanos NK.

Atherosclerosis. 2001 Feb 1;154(2):367-76.

Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide composition.

Theocharis AD, Tsara ME, Papageorgacopoulou N, Karavias DD, Theocharis DA.

Biochim Biophys Acta. 2000 Oct 18;1502(2):201-6.

Isolation and analysis of a novel acidic polysaccharide from the case of squid pen.

Theocharis AD, Karamanos NK, Tsegenidis T.

Int J Biol Macromol. 1999 Oct;26(1):83-8.

Human abdominal aortic aneurysm is closely associated with compositional and specific structural modifications at the glycosaminoglycan level.

Theocharis AD, Tsolakis I, Tsegenidis T, Karamanos NK.

Atherosclerosis. 1999 Aug;145(2):359-68.