Biochemistry, Biochemical Analysis & Matrix Pathobiology Research Group


UVB-mediated down-regulation of proteasome in cultured human primary pterygium fibroblasts.

Aletras AJ, Trilivas I, Christopoulou ME, Drakouli S, Georgakopoulos CD, Pharmakakis N.

BMC Ophthalmol. 2018 Dec 18;18(1):328. doi: 10.1186/s12886-018-0987-8.

Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.

Bouris P, Skandalis SS, Piperigkou Z, Afratis N, Karamanou K, Aletras AJ, Moustakas A, Theocharis AD, Karamanos NK.

Matrix Biol. 2015 Apr;43:42-60. doi: 10.1016/j.matbio.2015.02.008. Epub 2015 Feb 27.

Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.

Theocharis AD, Gialeli C, Bouris P, Giannopoulou E, Skandalis SS, Aletras AJ, Iozzo RV, Karamanos NK.

FEBS J. 2014 Nov;281(22):5023-42. doi: 10.1111/febs.12927. Epub 2014 Nov 6. Review.

EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules.

Ellina MI, Bouris P, Aletras AJ, Theocharis AD, Kletsas D, Karamanos NK.

Biochim Biophys Acta. 2014 Aug;1840(8):2651-61. doi: 10.1016/j.bbagen.2014.04.019. Epub 2014 May 2.

Detection of a latent soluble form of membrane type 1 matrix metalloprotease bound with tissue inhibitor of matrix metalloproteinases-2 in periprosthetic tissues and fluids from loose arthroplasty endoprostheses.

Niarakis A, Giannopoulou E, Ravazoula P, Panagiotopoulos E, Zarkadis IK, Aletras AJ.

FEBS J. 2013 Dec;280(24):6541-55. doi: 10.1111/febs.12555. Epub 2013 Oct 25.

Extracellular matrix degradation and tissue remodeling in periprosthetic loosening and osteolysis: focus on matrix metalloproteinases, their endogenous tissue inhibitors, and the proteasome.

Syggelos SA, Aletras AJ, Smirlaki I, Skandalis SS.

Biomed Res Int. 2013;2013:230805. doi: 10.1155/2013/230805. Epub 2013 Jun 19. Review.

MIF attenuates the suppressive effect of dexamethasone on IL-6 production by nasal polyp.

Stathas T, Athanassiou SD, Drakouli S, Giannopoulou E, Mastronikolis NS, Naxakis S, Aletras AJ.

Eur Rev Med Pharmacol Sci. 2013 Jun;17(11):1455-66.

Presence of hyaluronidase isoforms in nasal polyps.

Hatziri A, Vynios DH, Panogeorgou T, Bouga H, Triantaphyllidou IE, Naxakis SS, Stathas T, Aletras AJ, Kourousis C, Mastronikolis NS.

Eur Rev Med Pharmacol Sci. 2013 Jan;17(2):247-52.

Targeting the tumor proteasome as a mechanism to control the synthesis and bioactivity of matrix macromolecules.

Skandalis SS, Aletras AJ, Gialeli C, Theocharis AD, Afratis N, Tzanakakis GN, Karamanos NK.

Curr Mol Med. 2012 Sep;12(8):1068-82. Review.

A proposed mechanism for the inhibitory effect of the anticancer agent titanocene dichloride on tumour gelatinases and other proteolytic enzymes.

Pavlaki M, Debeli K, Triantaphyllidou IE, Klouras N, Giannopoulou E, Aletras AJ.

J Biol Inorg Chem. 2009 Aug;14(6):947-57. doi: 10.1007/s00775-009-0507-7. Epub 2009 Apr 24.

Walker 256 cancer cells secrete tissue inhibitor of metalloproteinase-free metalloproteinase-9.

Pavlaki M, Giannopoulou E, Niarakis A, Ravazoula P, Aletras AJ.

Mol Cell Biochem. 2009 Aug;328(1-2):189-99. doi: 10.1007/s11010-009-0089-2. Epub 2009 Mar 29.